Quality Control of Methyl 2-(1-methyl-1H-pyrrol-2-yl)acetate. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: Methyl 2-(1-methyl-1H-pyrrol-2-yl)acetate, is researched, Molecular C8H11NO2, CAS is 51856-79-2, about Friedel-Crafts Acylation of Pyrroles and Indoles using 1,5-Diazabicyclo[4.3.0]non-5-ene (DBN) as a Nucleophilic Catalyst. Author is Taylor, James E.; Jones, Matthew D.; Williams, Jonathan M. J.; Bull, Steven D..
1,5-Diazabicyclo[4.3.0]non-5-ene (DBN) has been shown to be an effective catalyst for the regioselective Friedel-Crafts C-acylation of pyrroles and indoles in high yields. A detailed mechanistic study implies that DBN is acting as a nucleophilic organocatalyst, and the X-ray crystal structure of a key N-acyl-amidine intermediate have been determined for the first time.
《Friedel-Crafts Acylation of Pyrroles and Indoles using 1,5-Diazabicyclo[4.3.0]non-5-ene (DBN) as a Nucleophilic Catalyst》 provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound(Methyl 2-(1-methyl-1H-pyrrol-2-yl)acetate)Quality Control of Methyl 2-(1-methyl-1H-pyrrol-2-yl)acetate.
Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem