Synthetic Route of C8H11NO2. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: Methyl 2-(1-methyl-1H-pyrrol-2-yl)acetate, is researched, Molecular C8H11NO2, CAS is 51856-79-2, about Reaction of substituted N-methylbenzimidoyl chlorides with pyrrole-2-acetate esters. Author is Mills, John E.; Cosgrove, Robin M.; Shah, Rekha D.; Maryanoff, Cynthia A.; Paragamian, Vasken.
4-RC6H4CCl:NMe (I; R = H, Me, OMe, Cl, NO2) react with pyrroleacetates II (R1 = H, Me) to give 30-69% ketimines III. The acid-catalyzed substitution is enhanced by electron-withdrawing substituents and retarded by electron-donating substituents on I.
《Reaction of substituted N-methylbenzimidoyl chlorides with pyrrole-2-acetate esters》 provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound(Methyl 2-(1-methyl-1H-pyrrol-2-yl)acetate)Synthetic Route of C8H11NO2.
Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem