The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 4-(((1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl)oxy)-4-oxobutanoic acid( cas:77341-67-4 ) is researched.Electric Literature of C14H24O4.Omata, Tetsuo; Iwamoto, Noritada; Kimura, Tomio; Tanaka, Atsuo; Fukui, Saburo published the article 《Stereoselective hydrolysis of dl-menthyl succinate by gel-entrapped Rhodotorula minuta var. texensis cells in organic solvent》 about this compound( cas:77341-67-4 ) in European Journal of Applied Microbiology and Biotechnology. Keywords: heptane menthol succinate Rhodotorula; polyurethane menthol succinate Rhodotorula; resolution menthol succinate Rhodotorula. Let’s learn more about this compound (cas:77341-67-4).
The compound dl-menthyl succinate [75363-56-3] was hydrolyzed stereoselectively by R. minuta texensis cells trapped in photo-crosslinked or polyurethane resin gels in water-saturated n-heptane [142-82-5]. The hydrolyzed product was pure l-menthol [2216-51-5]. The catalytic activity of the immobilized cells, especially those trapped in urethane polymers, was far more stable than that of the free cells. The 1/2-life of the polyurethane-entrapped cells was 55-63 days in the organic solvent.
Different reactions of this compound(4-(((1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl)oxy)-4-oxobutanoic acid)Electric Literature of C14H24O4 require different conditions, so the reaction conditions are very important.
Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem