Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: Methyl 2-(1-methyl-1H-pyrrol-2-yl)acetate, is researched, Molecular C8H11NO2, CAS is 51856-79-2, about Reaction of pyrroles with naphthoquinones. Synthesis of new pyrrolylnaphthoquinone dyes.Synthetic Route of C8H11NO2.
The reaction of 1,4-naphthoquinone with N-alkylpyrroles gives a mixture of 2-(pyrrol-2-yl)-1,4-naphthoquinones and 2,5-bis(1,4-naphthoquinon-2-yl)pyrroles. The yields and the ratios of these two products depend greatly on the exptl. conditions. The reaction has been extended to 5-hydroxy-1,4-naphthoquinone and 1,2-naphthoquinone. New pyrrolylnaphthoquinone dyes are obtained.
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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem