In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called In vitro DNA synthesis. DNA activation necessary for the reaction by liver-homogenate supernatants in compensatory hypertrophy and hepatoma. Implicated enzymic mechanisms, published in 1964, which mentions a compound: 3066-84-0, mainly applied to , Reference of 8-Bromoguanine.
cf. CA 62, 3181g. The progressive transformation of native DNA into primer DNA in the presence of rat liver homogenate supernatants previously reported has been shown not to be due to action of the DNases I and II of these supernatants, but should probably be attributed to an enzyme of the type DNA-phosphatase-exonuclease, described by Richardson, et al. (CA 60, 5810f).
After consulting a lot of data, we found that this compound(3066-84-0)Reference of 8-Bromoguanine can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem