The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: (S)-Butan-2-ol( cas:4221-99-2 ) is researched.Category: tetrahydrofurans.Kilic, Ahmet; Balci, Tugba Ersayan; Arslan, Nevin; Aydemir, Murat; Durap, Feyyaz; Okumus, Veysi; Tekin, Recep published the article 《Synthesis of cis-1,2-diol-type chiral ligands and their dioxaborinane derivatives: Application for the asymmetric transfer hydrogenation of various ketones and biological evaluation》 about this compound( cas:4221-99-2 ) in Applied Organometallic Chemistry. Keywords: diol chiral ligand dioxaborinane preparation radical scavenging antibacterial; reducing power DNA binding cleavage diol chiral ligand dioxaborinane; chiral stereoselective transfer hydrogenation ketone diol chiral ligand dioxaborinane. Let’s learn more about this compound (cas:4221-99-2).
Two cis-1,2-diol-type chiral ligands (T1 and T2) and their tri-coordinated chiral dioxaborinane (T(1-2)B(1-2)) and four-coordinated chiral dioxaborinane adducts with 4-tert-Bu pyridine sustained by N → B dative bonds (T(1-2)B(1-2)-N) were synthesized and characterized by various spectroscopic techniques such as NMR (1H, 13C, and 11B), FT-IR and UV-Vis spectroscopy, LC-MS/MS, and elemental anal. It was suggested that both ferrocene and trifluoromethyl groups played key roles in the catalytic and biol. studies because they could tune the solubility of the chiral dioxaborinane complexes and adjust the strength of intermol. interactions. To assess the biol. activities of newly synthesized chiral dioxaborinane compounds, DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging, reducing power, antibacterial, DNA binding, and DNA cleavage activities were tested. Then, all chiral dioxaborinane complexes were investigated as catalysts for the asym. transfer hydrogenation of various ketones under suitable conditions. The results indicated that the chiral dioxaborinane catalysts performed well with high yields.
After consulting a lot of data, we found that this compound(4221-99-2)Category: tetrahydrofurans can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem