Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 26218-78-0, is researched, SMILESS is C1=NC(=CC=C1C(=O)OC)Br, Molecular C7H6BrNO2Journal, Heterocycles called Synthesis of pyrrolo[2,3-d]pyrimidine analogues: “”pyridine ring”” analogues of pemetrexed, Author is Xu, Yun; Yu, Mingfeng; Long, Yan; Wu, Han; Mao, Zhenmin, the main research direction is pyridine analog pemetrexed preparation anticancer.Category: tetrahydrofurans.
Two analogs of pemetrexed with its Ph ring replaced with a pyridine ring were synthesized as novel anticancer agents. Preliminary in-vitro evaluation indicated that replacement of the Ph moiety of pemetrexed by the pyridine ring with the 6-5 bicyclic ring system showed low cytotoxicity, that departs from the findings with antifolates bearing a 6-6 bicyclic system.
After consulting a lot of data, we found that this compound(26218-78-0)Category: tetrahydrofurans can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem