Padula, Daniele; Mazzeo, Giuseppe; Santoro, Ernesto; Scafato, Patrizia; Belviso, Sandra; Superchi, Stefano published the article 《Amplification of the chiroptical response of UV-transparent amines and alcohols by N-phthalimide derivatization enabling absolute configuration determination through ECD computational analysis》. Keywords: amine alc phthalimide conformer optical activity UV CD spectra.They researched the compound: (S)-Butan-2-ol( cas:4221-99-2 ).Recommanded Product: 4221-99-2. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:4221-99-2) here.
The stereoselective transformation of chiral UV-transparent amines and alcs. to phthalimides has proved to be a simple and efficient method to enhance the chiroptical response of these substrates allowing their reliable absolute configuration determination by computational anal. of ECD spectra. Such a transformation also leads to a significant reduction in the mol. conformational flexibility thus simplifying the conformational anal. required by the computational treatment. The method described herein thus allows the absolute configuration assignment to these challenging substrates to be much easier and reliable.
As far as I know, this compound(4221-99-2)Recommanded Product: 4221-99-2 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem