An update on the compound challenge: 4221-99-2

As far as I know, this compound(4221-99-2)Computed Properties of C4H10O can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Computed Properties of C4H10O. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: (S)-Butan-2-ol, is researched, Molecular C4H10O, CAS is 4221-99-2, about Nickel-Catalyzed Enantioconvergent Reductive Hydroalkylation of Olefins with α-Heteroatom Phosphorus or Sulfur Alkyl Electrophiles. Author is He, Shi-Jiang; Wang, Jia-Wang; Li, Yan; Xu, Zhe-Yuan; Wang, Xiao-Xu; Lu, Xi; Fu, Yao.

Substantial advances in enantioconvergent C(sp3)-C(sp3) bond formation reactions have been made in recent years through the use of transition-metal-catalyzed cross-coupling reactions of racemic secondary alkyl electrophiles with organometallic reagents. Herein, we report a general process for the asym. construction of alkyl-alkyl bonds adjacent to heteroatoms, namely, a nickel-catalyzed enantioconvergent reductive hydroalkylation of olefins with α-heteroatom phosphorus or sulfur alkyl electrophiles. Including the use of readily available olefins, this reaction has considerable advantages, such as mild reaction conditions, a broad substrate scope, and good functional group compatibility, making it a desirable alternative to traditional electrophile-nucleophile cross-coupling reactions.

As far as I know, this compound(4221-99-2)Computed Properties of C4H10O can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem