Winde, Ekkehard published an article about the compound: 1-Hexyl-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione( cas:1028-33-7,SMILESS:CN1C=NC(N(C(N2CCCCCC)=O)C)=C1C2=O ).Quality Control of 1-Hexyl-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:1028-33-7) through the article.
A Rotating Dissolution cell (RD-cell), based on the flow-through principle, is presented for the determination of the dissolution rates of drugs from oral solid dosage forms. Due to the rotational movement of the cell, a liquid current is generated perpendicular to the direction of the flow of the test medium. Thereby the mech. stress on the dosage form becomes nearly independent on the flow rate of the medium and may be varied by adjusting the speed of rotation. The all-glass construction eliminates the absorption of dissolved drug by plastics used in other testing devices, such as membrane filters and tubes. The cell is especially suitable for testing sustained-release dosage forms as demonstrated by results from 14 com. preparations These included various retard principles, such as diffusion pellets, imbedments, matrixes and ion exchange. The release profiles obtained with the RD-cell are reproducible and provide a measure for the pharmaceutical equivalence of similar dosage forms.
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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem