Safety of 4-(((1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl)oxy)-4-oxobutanoic acid. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: 4-(((1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl)oxy)-4-oxobutanoic acid, is researched, Molecular C14H24O4, CAS is 77341-67-4, about Design and synthesis of potential fungicidal compounds derived from natural products, (-)-menthol and (-)-borneol. Author is Zhang, Tianyuan; Zheng, Shumin; You, Shuyan; Huang, Danling; Cheng, Yong-Xian.
Twelve Novel compounds I[ R1=R2 = H, CH3, Cl etc], II[ R1= R2 = H, CH3, Cl etc] derived from (-)-menthol and (-)-borneol were designed, synthesized and characterized by 1H NMR, 13C NMR, and HRMS. The fungicidal activities of these novel compounds I and II against Botrytis cinerea, Curvularia lunata and Alternaria alternata were evaluated. The results indicated that II[ R1 = R2 = F] displayed potential fungicidal activities against B. cinerea and C. lunata. Especially, II[ R1 = R2 = F] exhibited IC50 value of 22.9 mg/L against C. lunata, which was higher fungicidal activity than com. product hymexazol and amicarthiazol. In addition, the superficial structure-activity relationship were discussed. This study provided a structural template for the design of novel fungicides.
In addition to the literature in the link below, there is a lot of literature about this compound(4-(((1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl)oxy)-4-oxobutanoic acid)Safety of 4-(((1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl)oxy)-4-oxobutanoic acid, illustrating the importance and wide applicability of this compound(77341-67-4).
Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem