The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Pharmacology of 1-hexyl-3,7-dimethylxanthine》. Authors are Ramos, A. O.; Ramos, L.; Zanini, A. C.; Slemer, O..The article about the compound:1-Hexyl-3,7-dimethyl-1H-purine-2,6(3H,7H)-dionecas:1028-33-7,SMILESS:CN1C=NC(N(C(N2CCCCCC)=O)C)=C1C2=O).Related Products of 1028-33-7. Through the article, more information about this compound (cas:1028-33-7) is conveyed.
1-Hexyl-3,7-dimethylxanthine (HeX) inhibited contractions induced by acetylcholine, pilocarpine, and BaCl2 in the isolated rat duodenum and guinea pig ileum and trachea. HeX did not cause hypotension, but caused a marked, prolonged pial vasodilation in dogs. In rats HeX induced a diuresis.
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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem