Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 1028-33-7, is researched, Molecular C13H20N4O2, about Glucose transport into the brain. Its dependency on blood glucose level and its modification by drugs, the main research direction is glucose uptake brain; blood brain barrier glucose; insulin glucose brain; glucagon glucose brain.Related Products of 1028-33-7.
Glucose (I) [50-99-7] uptake into the brain of mice was probably independent of the blood I level over the measured range of 50-300 mg% and proceeded via a facilitated, i.e. passive, carrier-mediated transport mechanism. Insulin [9004-10-8], Helfergin [51-68-3], and 1-ethyltheophylline [37102-58-2] increased the I uptake after i.v. administration of U-14C-labeled I to mice, whereas glucagon [9007-92-5], γ-hydroxybutyric acid [591-81-1], and Cosaldon [1028-33-7] decreased it. The other compounds investigated were inactive. However, these alterations in I uptake were not real, because the uptake of radioactivity into the brain was reciprocal to the blood I level in accordance with the expected change of sp. activity when a constant quantity of external radioactive I was mixed with the inactive blood.
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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem