Continuously updated synthesis method about 76632-23-0

From this literature《Synthesis and cytotoxic evaluation of some structural fragments of epothilone A》,we know some information about this compound(76632-23-0)Recommanded Product: 76632-23-0, but this is not all information, there are many literatures related to this compound(76632-23-0).

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Synthesis and cytotoxic evaluation of some structural fragments of epothilone A, published in 2002-09-30, which mentions a compound: 76632-23-0, mainly applied to epothilone A fragment preparation cytotoxicity, Recommanded Product: 76632-23-0.

The epothilones are a series of macrocyclic lactones with cytotoxic activity. Fragments of epothilone A were prepared and evaluated for cytotoxic activity in order to try to determine the active part of the epothilone structure. The fragments prepared, I [R = HOCHMe, tetrahydro-2-pyranyl, HOCHMeCH2CO2CH2, Me2CH(CH2)3CH:CH(CH2)2 (5)] and 5 diepoxide, did not display bioactivity.

From this literature《Synthesis and cytotoxic evaluation of some structural fragments of epothilone A》,we know some information about this compound(76632-23-0)Recommanded Product: 76632-23-0, but this is not all information, there are many literatures related to this compound(76632-23-0).

Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem