Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 3066-84-0, is researched, Molecular C5H4BrN5O, about Effect of Different Z-Inducers on the Stabilization of Z Portion in BZ-DNA Sequence: Correlation Between Experimental and Simulation Data, the main research direction is B Z DNA conformation free energy mol dynamics simulation; B-Z junction; DNA; chirality index; circular dichroism; free energy calculation.Quality Control of 8-Bromoguanine.
In this study we show the outstanding agreement between simulation and exptl. data concerning the efficient stabilization effect by NaCl of Z conformation. We demonstrate by CD (CD) experiments that Na+ not only is able to induce a B to Z form transition in a short (GC)3 alternated portion of a sequence having 17 basis, but also is the best stabilizer in comparison with other Z inducers used (spermine and NiCl2). This result was confirmed by free energy calculations
In some applications, this compound(3066-84-0)Quality Control of 8-Bromoguanine is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem