Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 2-Amino-5-chlorobenzaldehyde, is researched, Molecular C7H6ClNO, CAS is 20028-53-9, about An Improved Protocol for the Synthesis of Quinoline-2,3-dicarboxylates under Neutral Conditions via Biomimetic Approach.Safety of 2-Amino-5-chlorobenzaldehyde.
A mild and efficient protocol for synthesis of quinoline-2,3-dicarboxylates in aqueous medium under neutral conditions via heterocyclization of ortho-aminoaryl ketones with acetylenedicarboxylates is described. The reaction proceeded smoothly in H2O catalyzed by supramol. catalyst β-CD.
In some applications, this compound(20028-53-9)Safety of 2-Amino-5-chlorobenzaldehyde is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem