Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 20028-53-9, is researched, SMILESS is NC1=CC=C(Cl)C=C1C=O, Molecular C7H6ClNOJournal, Article, Research Support, N.I.H., Extramural, Journal of Organic Chemistry called Synthesis of Acridines by the [4 + 2] Annulation of Arynes and 2-Aminoaryl Ketones, Author is Rogness, Donald C.; Larock, Richard C., the main research direction is trimethylsilylaryl triflate cesium fluoride generated aryne aminoaryl ketone cycloaddition; substituted acridine preparation crystal mol structure.Quality Control of 2-Amino-5-chlorobenzaldehyde.
The reaction of 2-aminoaryl ketones and arynes generated by the treatment of various o-(trimethylsilyl)aryl triflates with CsF resulted in [4 + 2]-annulation to afford substituted acridines, e.g., I (R = H, Cl), in good yields.
In some applications, this compound(20028-53-9)Quality Control of 2-Amino-5-chlorobenzaldehyde is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem