The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Preparation and characterization of a new bis-layered supported ionic liquid catalyst (SILCA) with an unprecedented activity in the Heck reaction》. Authors are Vucetic, Nemanja; Virtanen, Pasi; Nuri, Ayat; Mattsson, Ida; Aho, Atte; Mikkola, Jyri-Pekka; Salmi, Tapio.The article about the compound:Methyl 6-bromonicotinatecas:26218-78-0,SMILESS:C1=NC(=CC=C1C(=O)OC)Br).Formula: C7H6BrNO2. Through the article, more information about this compound (cas:26218-78-0) is conveyed.
A new bis-layered supported ionic liquid catalyst (SILCA) loaded with Pd was designed and applied for the Heck reaction of iodobenzene and Me acrylate. The SiO2 modified catalyst consisting of the 1st ionic liquid layer – covalently anchored imidazolium bromide – on which the 2nd layer, made of pyridine-carboxylic acid balanced with tetramethylguanidinium cation was attached, resulted in a catalyst with high activity. High turnover frequencies of 22,000 h-1 were achieved in reactions with a low Pd loading as 0.009 mol %. Lower TOFs, indicating on Pd dimerization was detected when higher amounts were used. The TMG cation had a purpose to recapture and stabilize the Pd nanoparticles thus followed a release and catch mechanism. To get a full understanding of the catalyst structure and behavior, the catalyst was characterized by N physisorption, TGA, IR spectroscopy, scanning electron and transmission electron microscopes, solid-state NMR, XPS and inductively coupled plasma spectroscopy. The catalyst preserved good activity in 5 cycles.
In some applications, this compound(26218-78-0)Formula: C7H6BrNO2 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem