Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 51856-79-2, is researched, SMILESS is O=C(OC)CC1=CC=CN1C, Molecular C8H11NO2Journal, ARKIVOC (Gainesville, FL, United States) called Synthesis and biological evaluation of substituted naphthoquinone derivatives as potent antimycobacterial agents, Author is Mital, A.; Negi, V. S.; Ramachandran, U., the main research direction is naphthoquinone preparation antimycobacterial.Recommanded Product: Methyl 2-(1-methyl-1H-pyrrol-2-yl)acetate.
A series of 1,4-naphthoquinone derivatives were synthesized and screened for antitubercular activity against Mycobacterium tuberculosis H37Rv strain by the broth microdilution assay method. The in vitro antitubercular activity was moderate to good activity compared to reference drugs. The most effective compounds had IC50 values of 3.9-0.3 μg/mL.
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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem