Reference of 52079-23-9, In chemical reaction engineering, simulations are useful for investigating and optimizing a particular reaction process or system.
A stereoselective route to (1S, 8aS)-1-hydroxyindolizidine is reported herein that incorporates as a pivotal step the diastereoselective addition of the dianion of 4-(phenylsulfonyl)butanoic acid (4-PSBA) to a chiral alpha-benzyloxymethyl imine.
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Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem