Electric Literature of 15833-61-1, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 15833-61-1, (Tetrahydrofuran-3-yl)methanol, introducing its new discovery.
The invention discloses a method for synthesizing S-(+)-tetrahydrofuran-3-methanol. The method comprises the following steps: reacting D (+)-10-camphorsulfonic acid with thionyl chloride, so as to obtain D-(+)-10-camphor sulfonyl chloride; reacting D-(+)-10-camphor sulfonyl chloride with (+/-)-tetrahydrofuran-3-methanol, so as to obtain tetrahydrofuran-3-methyl camphor sulphonate; standing tetrahydrofuran-3-methyl camphor sulphonate to crystallize, performing configuration inversion in the crystallization process, so as to obtain tetrahydrofuran-3-methyl camphor sulphonate of single configuration, dissociating the crystal by using a dissociation agent, so as to obtain S-(+)-tetrahydrofuran-3-methanol. By adopting the method, the phenomenon that only 50% of single configuration can be obtained in the chiral resolution process is avoided, the yield is greatly increased, the synthesis route is short, and the operation is simple. The method is mainly applied to synthesis of a midbody, namely, S-(+)-tetrahydrofuran-3-methanol.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Electric Literature of 15833-61-1. In my other articles, you can also check out more blogs about 15833-61-1
Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem