Chemistry is traditionally divided into organic and inorganic chemistry. Quality Control of (S)-4-Hydroxydihydrofuran-2(3H)-one, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 7331-52-4
A process for preparing a 3-hydroxy-gamma-butyrolactone derivative represented by the following formula (1): wherein R is C1-C6 alkyl, 3 to 6-membered cycloalkyl, aralkyl, 2-alkenyl, acyl, alpha-hydroxyalkyl, alkoxycarbonylalkyl or alkoxycarbonyl, which is characterized in treating 3-hydroxy-gamma-butyrolactone with a metal salt of hexamethyldisilazane and then, reacting it with an electrophilic reagent, optionally in the presence of a reaction promoter.
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Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem