Related Products of 915095-89-5, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.915095-89-5, Name is (S)-3-(4-(5-Bromo-2-chlorobenzyl)phenoxy)tetrahydrofuran, molecular formula is C17H16BrClO2. In a Patent，once mentioned of 915095-89-5
The method comprises, in the presence of a co-solvent, raw material aryl bromide (Canagliflozin), and an organolithium reagent to undergo nucleophilic addition reaction to obtain the key intermediate (Dapagliflozin) of combagliflozin (Empagliflozin) and. (C – 1, D – 1. The method disclosed E – 1) is beneficial to preparation of final product.1). The method can stereoselectively synthesize and obtain the key intermediate, of comb. 2 by nucleophilic addition reaction to obtain a key intermediate 3, of combagliflozin-TMS and is shown in the following step. 4. The method comprises the following steps: preparing a key intermediate of 5;2)5 g of glipizliflozin. TMS. The method comprises the following steps: preparing a key intermediate compound, (C – 1, D – 1 and a E – 1), 1. protecting (>75%), base, by nucleophilic addition reaction with an organic (HPLC lithium 95% reagent), in the presence of a co-solvent. (by machine translation)
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 915095-89-5
Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem