Related Products of 15833-61-1, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 15833-61-1, (Tetrahydrofuran-3-yl)methanol, introducing its new discovery.
The invention discloses a method for synthesis of dinotefuran, to gamma – butyrolactone as raw materials, by Aldol condensation, also the original two-step by the reaction of 3 – hydroxy methyl tetrahydrofuran, then by the Gabriel synthesis of 3 – tetrahydrofuran methyl amine, dimethyl carbonate (DMC) as methylation reagent with the urea synthesis O – methyl isourea, re-nitration synthetic O – methyl – N – nitro-isourea, then with the methylamine reaction synthesis of 1, 3 – dimethyl – 2 – nitro-isourea, final 3 – tetrahydrofuran methylamine with 1, 3 – dimethyl – 2 – nitro-isourea through SN2 Bimolecular nucleophilic substitution reaction, one-step synthesis of dinotefuran. The present invention uses non of dimethyl carbonate as the methylating reagent, the methylation reaction yield ? 95%, O – methyl isourea content ? 96%, the by-product is carbon dioxide and methanol, process and environmental protection, the overall yield of the dinotefuran ? 50%. Synthetic method of this invention to reduce the production cost at the same time, with three wastes, after treatment is simple, the advantages of the environment friendly, and is suitable for industrial production, bring about significant economic benefits. (by machine translation)
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Related Products of 15833-61-1. In my other articles, you can also check out more blogs about 15833-61-1
Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem