Chemistry is traditionally divided into organic and inorganic chemistry. Quality Control of 4,4-Dimethyldihydrofuran-2,3-dione, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 13031-04-4
The Noyori-Ikariya catalysts, Ru-TsDPEN 1 or 2,in combination with HCOOH/Hunig’s base (5:2) have been successfully utilized for catalytic asymmetric transfer hy-drogenation of alpha-ketopantolactam, and optically enriched N-substituted pantolactam was prepared (S/C = 500, up to 95% ee and 99% conversion in HCOOH/Hunig’s base condition). More than 2 kg of this key intermediate 9 has been synthesized efficiently with excellent chemical yield and chiral purity.
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Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem