One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Product Details of 915095-89-5, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 915095-89-5, Name is (S)-3-(4-(5-Bromo-2-chlorobenzyl)phenoxy)tetrahydrofuran, molecular formula is C17H16BrClO2
Empagliflozin, (2S,3R,4R,5S,6R)-2-[4-chloro-3-[[4-[(3S)-oxolan-3-yl]oxyphenyl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5- triol was recently approved by the FDA for the treatment of chronic type 2 diabetes mellitus. Herein, we report the synthesis of carbon-13 and carbon-14 labeled empagliflozin. Carbon-13 labeled empagliflozin was prepared in five steps and in 34% overall chemical yield starting from the commercially available a-D-glucose-[13C6]. For the radiosynthesis, the carbon-14 atom was introduced in three different positions of the molecule. In the first synthesis, Carbon-14 D-(+)-gluconic acid delta-lactone was used to prepare specifically labeled empagliflozin in carbon-1 of the sugar moiety in four steps and in 19% overall radiochemical yield. Carbon-14 labeled empagliflozin with the radioactive atom in the benzylic position was obtained in eight steps and in 7% overall radiochemical yield. In the last synthesis carbon-14 uniformly labeled phenolwas used to give [14C]empagliflozin in eight steps and in 18% overall radiochemical yield. In all these radiosyntheses, the specific activities of the final compounds were higher than 53 mCi/mmol, and the radiochemical purities were above 98.5%.
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Safety of (S)-3-(4-(5-Bromo-2-chlorobenzyl)phenoxy)tetrahydrofuran, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 915095-89-5
Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem