17347-61-4, Name is 2,2-Dimethylsuccinicanhydride, belongs to tetrahydrofurans compound, is a common compound. Computed Properties of C6H8O3In an article, once mentioned the new application about 17347-61-4.
Screening of the Maybridge compound collection identified 4-arylphthalazinones as micromolar inhibitors of PARP-1 catalytic activity. Subsequent optimisation of both inhibitory activity and metabolic stability led to a novel series of meta-substituted 4-benzyl-2H-phthalazin-1-ones with low nanomolar, cellular activity as PARP-1 inhibitors and promising metabolic stability in vitro.
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Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem