More research is needed about 4,4-Dimethyldihydrofuran-2,3-dione

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The process parameters of dehydrogenation of pantolactone with bromine in chloroform and the possibility of bromine recycling by electrolysis of hydrogen bromide formed in the synthesis of ketopanto-lactone were studied.

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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

The Absolute Best Science Experiment for Dihydrofuran-3(2H)-one

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Substituted spirocyclic tetrahydropyranyl mesylates and tosylates have been synthesized in good yields using a Prins-type cyclization of various cyclic ketones, a homoallylic alcohol and either methanesulfonic or p-toluenesulfonic acid under non-aqueous conditions. The mesylates thus produced could then be transformed into the corresponding Boc-protected amines using an efficient two step procedure.

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Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

More research is needed about (Tetrahydrofuran-3-yl)methanol

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In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Recommanded Product: 15833-61-1, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 15833-61-1, name is (Tetrahydrofuran-3-yl)methanol. In an article,Which mentioned a new discovery about 15833-61-1

Possible structures and modes of formation of C4H7O(1+) ions formed by electron impact induced decomposition of tetrahydrofuran and tetrahydropyran derivates are discussed in view of labelling results and MIKE, CA, and T data.Limitations of these techniques are pointed out.

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Extracurricular laboratory:new discovery of 453-20-3

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GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein Ar, B, R 1, R 2, R 3a, R 3b, R 4, R 5, R 6 and m are as defined herein.

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Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Awesome Chemistry Experiments For 22929-52-8

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Electric Literature of 22929-52-8, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 22929-52-8, Name is Dihydrofuran-3(2H)-one,introducing its new discovery.

The present invention provides triazolopyrazinones as PDE1 inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative disorders and psychiatric disorders.

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Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Awesome and Easy Science Experiments about (S)-(-)-alpha-Hydroxy-gamma-butyrolactone

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Application of 52079-23-9, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.52079-23-9, Name is (S)-(-)-alpha-Hydroxy-gamma-butyrolactone, molecular formula is C4H6O3. In a article,once mentioned of 52079-23-9

The homochiral 1,3-dioxanes 8a-e with a 2-bromophenyl substituent in position 2 and an electrophilic group in position 4 were stereo- and regioselectively prepared from the (S)-malic acid derivatives 6a, 6b, 11, and 14. Attempts to prepare the tricycles 5a-c by connecting the 2-phenyl substituent with the electrophilic groups in position 4 of 8a-e in a Parham cyclization across the 1,3-dioxane ring failed. The synthesis of the tricyclic title ketone 5a succeeded, however, by addition of the lithiated benzaldehyde acetal 7c to the protected alpha-hydroxylactone 10b and subsequent treatment of the intermediate ketone 23 with acid. The acid hydrolysis of the alcohol 26, which was obtained by addition of 7c to the protected dihydroxy aldehyde 25b, followed by oxidation of the resulting alcohols 27 a and b represent a second possibility for the preparation of the tricyclic ketone 5a. VCH Verlagsgesellschaft mbH, 1996.

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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Brief introduction of 3-Methyldihydrofuran-2(3H)-one

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An electron-deficient amide is utilized as a directing group to functionalize nonactivated C(sp3)-H bonds through radical 1,5-hydrogen abstraction. The gamma-bromoamides formed are subsequently converted to gamma-lactones under mild conditions. The method described is not limited to tertiary and secondary positions but also allows functionalization of primary nonactivated sp3-hybridized positions in a one-pot sequence. In addition, the broad functional group tolerance renders this method suitable for the late-stage introduction of gamma-lactones into complex carbon frameworks.

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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

More research is needed about (S)-(Tetrahydrofuran-2-yl)methanol

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Naftidrofuryl oxalate (Praxilene, 1) has been used for the treatment of intermittent claudication for more than 30 years. It selectively blocks vascular and platelet 5-hydroxytryptamine 2 (5-HT2) receptors. This drug is marketed as a mixture of four stereoisomers, and so far there is no individual biological evaluation on the single isomers. The purpose of this study is to provide an improved method for the preparation of all four stereoisomers of naftidrofuryl, and more importantly, to distinguish them in terms of their binding affinity to 5-hydroxytryptamine 2A (5-HT2A) receptor. The bioassay results revealed that the C-2S configuration of naftidrofuryl was crucial for the binding affinity with 5-HT2A receptor, and the C-2? configuration was less important for binding. In conclusion, our study may pave the way to develop single naftidrofuryl isomers with C-2S configuration as inhibitors of 5-HT2A receptor that have clinical significance as vasodilators and CNS agents.

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Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Awesome and Easy Science Experiments about 453-20-3

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453-20-3, Name is 3-Hydroxytetrahydrofuran, belongs to tetrahydrofurans compound, is a common compound. Application In Synthesis of 3-HydroxytetrahydrofuranIn an article, once mentioned the new application about 453-20-3.

The present invention relates to compounds of formula (I): or pharmaceutically acceptable salts thereof, wherein R1, R2, X, Y, and HET are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes

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Tetrahydrofuran – Wikipedia,
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Can You Really Do Chemisty Experiments About (R)-(+)-2-Tetrahydrofuroic acid

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The invention provides novel benzoimidazolone-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.

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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem