21461-84-7, Name is (S)-( )-5-Oxo-2-tetrahydrofurancarboxylic Acid, belongs to tetrahydrofurans compound, is a common compound. COA of Formula: C5H6O4In an article, once mentioned the new application about 21461-84-7.
(Chemical Equation Presented) A small library of chiral, beta3-substituted homopropargyl alcohols and chiral beta3-substituted trimethylsilylhomopropargyl azides were generated starting from natural L-amino acids. The free alkynes and azides were then coupled, using a Huisgen 1,3-dipolar cycloaddition, to provide chiral oligomeric 1,4-disubstituted-1,2,3-triazoles as potential peptidomimetic compounds. The work is an extension to the previous synthesis of racemic, orthogonally protected 1,4-disubstituted-1,2,3-triazoles from the corresponding alpha-substituted propargyl alcohols and alpha-substituted trialkylsilylpropargyl azides.
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Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem