Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. COA of Formula: C6H8O3. Introducing a new discovery about 17347-61-4, Name is 2,2-Dimethylsuccinicanhydride
An efficient asymmetric hydrogenation of beta,gamma-unsaturated gamma-lactams using an iridium-phosphoramidite complex is reported. The chiral gamma-lactams were obtained in excellent yields and enantioselectivities (up to 99% yield and 99% ee). The mechanistic studies indicated that the reduced products were obtained via the hydrogenation of the N-acyliminium cations, generated from beta,gamma-unsaturated gamma-lactams, which was verified by 1H NMR analysis. The reaction was carried out at a reduced catalyst loading of 0.1 mol %, and the reduced products can be transformed to two potential bioactive compounds. A new route is provided for the synthesis of chiral gamma-lactams.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.COA of Formula: C6H8O3, you can also check out more blogs about17347-61-4
Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem