Extracurricular laboratory:new discovery of 4-Benzyldihydrofuran-2(3H)-one

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Microbial Baeyer – Villiger oxidation of representative prochiral ketones with a cyclobutanone structural motif was investigated using a collection of eight monooxygenases of different bacterial origin. This platform of enzymes is able to perform stereoselective biotransformations on an array of structurally diverse substrates. With several ketone precursors, biooxidations yielded enantiocomplementary butyrolactones as key intermediates for the synthesis of natural products and bioactive compounds. The microbial Baeyer – Villiger oxidation allows a facile and rapid entry to several compound classes in a desymmetrization reaction upon de novo generation of chirality.

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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Brief introduction of 3-Bromotetrahydrofuran

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The invention provides compounds of Formula (I) as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and methods to use these compounds, salts and compositions for treating viral infections, particularly infections caused by hepatitis B virus, and reducing the occurrence of serious conditions associated with HBV.

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Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

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The rates of gas-phase thermolysis reactions of 2-acetylcyclopentanone 1, 2-acetylcyclohexanone 2, N-acetylcaprolactam 3, 2-acetylbutyrolactone 4, 2-acetyl-2-methylbutyrolactone 5, and 3-acetyl-2-oxazolidinone 6 have been measured over a temperature range of 50 K.They undergo unimolecular first-order elimination reactions for which log A = 11.7, 11.7, 11.2, 11.4, 11.5, and 11.1 s-1 and Ea = 193.4, 189.5, 153.2, 201.0, 206.8, and 176.1 kJ mol-1, respectively.The effect of the ring size together with the effect of a heteroatom in the ring on the rate of thermolysis reactions for compounds 1-6 is the subject of this work.

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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Simple exploration of (cis-Tetrahydrofuran-2,5-diyl)dimethanol

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Lignocellulosic biomass can be converted to significant platform molecule 5-hydroxymethylfurfural (HMF), from which one can envision a number of biofuels and chemicals through either chemical or biological conversions. Chemoselective hydrogenation is one of the important pathways for the upgrading of HMF into furanyl diols consisting of 2,5-bis(hydroxymethyl)furan (BHMF) and 2,5-bis(hydroxymethyl)tetrahydrofuran (BHMTHF). BHMF and BHMTHF are all-purpose intermediates for the manufacture of chemicals, fuels, and functional materials. In this context, we comprehensively summarized the studies on the chemoselective hydrogenation of HMF into furanyl diols in terms of different H-donors, including molecular H2, alcohols, formic acid, and other alternative H-donors. Through the systematic survey of the previous works, a feasible research direction is discussed for the production of furanyl diols.

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Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Awesome Chemistry Experiments For Dihydrofuran-3(2H)-one

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Disclosed herein are modulators of TRPV3 of formula (II): wherein G1, X1, X2, X3, X4, X5, G2, Ra, Rb, and u are as defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also presented.

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Tetrahydrofuran – Wikipedia,
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Commercially available N-Boc-4-O-benzyl-L-homoserine was treated with trifluoroacetic acid and the corresponding, N-deprotected derivative was submitted to deamination to give 4-O-benzyl-3-deoxy-L-glycero-tetronic acid (5). In another approach to 3-deoxy-L-glycero-tetronic acid protected at position 4, the carboxylic groups in L-malic acid were reduced, and the resulting triol was benzylidenated. Oxidation of the 2,4-O-benzylidene derivative formed with CrO3-pyridine complex in the presence of t-butyl alcohol gave t-butyl 2,4-O-benzylidene-3-deoxy-L-glycero-tetronate (13). The latter was saponified with aqueous sodium hydroxide to give, after Na+ exchange for H+, 2,4-O-benzylidene-3-deoxy-L-glycero-tetronic acid (15). Opening of the acetal ring in 13, followed by hydrolytic cleavage of the t-butyl ester function gave material indistinguishable from 5 obtained in the original way. When tested for their efficiency of N-acylation of derivatives of D-perosamine, both acids 5 and 15 gave the corresponding tetronamido derivatives in high yields.

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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Some scientific research about 4971-56-6

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Reference of 4971-56-6, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.4971-56-6, Name is Furan-2,4(3H,5H)-dione, molecular formula is C4H4O3. In a Article,once mentioned of 4971-56-6

A microwave-assisted regioselective synthesis of 3-functionalized indole derivatives via a three-component domino reaction of anilines, arylglyoxal monohydrates, and cyclic 1,3-dicarbonyl compounds is described. The main advantages of this protocol are short reaction times, practical simplicity, its metal-free nature, the availability of starting materials, green solvents, and high regioselectivity.

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Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

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Chiral bidentate amino(amido)phosphinephosphinite ligands (AMPP) have been used to synthesise new ruthenium bismethylallyl Ru(AMPP)(CH2C(CH3)CH2)2 and biscarboxylate Ru(AMPP)(OCOR)2 (R = CH3 or CF3) complexes.These complexes act as efficient catalyst precursors for the homogeneous asymmetric hydrogenation of alpha-ketoesters with enantiomeric excesses up to 79percent.

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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Discovery of 4971-56-6

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Application of 4971-56-6, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.4971-56-6, Name is Furan-2,4(3H,5H)-dione, molecular formula is C4H4O3. In a Review,once mentioned of 4971-56-6

Microorganisms are found everywhere, and they are closely associated with plants. Because the establishment of any plant-microbe association involves chemical communication, understanding crosstalk processes is fundamental to defining the type of relationship. Although several metabolites from plants and microbes have been fully characterized, their roles in the chemical interplay between these partners are not well understood in most cases, and they require further investigation. In this review, we describe different plant-microbe associations from colonization to microbial establishment processes in plants along with future prospects, including agricultural benefits.

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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Some scientific research about (S)-Benzyl (5-oxotetrahydrofuran-3-yl)carbamate

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This invention relates to N-{[(1S,4S,6S)-3-(2-pyridinylcarbonyl)-3-azabicyclo[4.1.0]hept-4-yl]methyl}-2-heteroarylamine derivatives and their use as pharmaceuticals.

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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem