In heterogeneous catalysis, the catalyst is in a different phase from the reactants. name: Tetrahydrofuran-3-carboxylic acid, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 89364-31-8, name is Tetrahydrofuran-3-carboxylic acid. In an article，Which mentioned a new discovery about 89364-31-8
An efficient and operationally simple synthesis of tetrahydrofuran-derived spiro-beta-lactams using the ketene-imine cycloaddition route is described. Also the preparation of spiro-N-sulfonyl-beta-lactam derivatives, which are analogs of monobactams, is reported. As far as we know, this is the first time that an unsymmetrical cyclic ketene is used in a Staudinger-type reaction. The experimental evidence suggests the involvement of a ketene derived from the acyl chloride precursor in the reaction. High-level ab initio calculations have been performed in order to get insight into the electronic effects controlling the stereochemical outcome of the reactions.
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Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem