7175-81-7, Name is (S)-(Tetrahydrofuran-2-yl)methanamine, belongs to tetrahydrofurans compound, is a common compound. Computed Properties of C5H11NOIn an article, once mentioned the new application about 7175-81-7.
A series of indolyl acrylamide derivatives was synthesized as potential diacylglycerol acyltransferase (DGAT) inhibitors. Furfurylamine containing indolyl acrylamide derivative 5h exhibited the most potent DGAT inhibitory activity using microsomes prepared from rat liver. Further evaluation against human DGAT-1 and DGAT-2 identified indolyl acrylamide analogues as selective inhibitors against human DGAT-2. In addition, the most potent compound 5h inhibited triglyceride synthesis dose-dependently in HepG2 cell lines. The Royal Society of Chemistry 2013.
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Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem