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[Problem] antiviral action, particularly anti-influenza drugs effective as the polycyclic pyridone derivative compound. (1) a compound represented by the formula [a]. (H or a prodrug group P is formed, A1 The CR are independently1A R1B , O or S; A2 The CR2A ; A3 The CR are independently3A R3B , O or S; A4 The CR4A ; A5 The CR are independently5A R5B , O or S; A6 Is a single bond or a substituted or unsubstituted alkylene substituted with hetero atoms/may be interposed)[Drawing] no (by machine translation)

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Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem