Day: May 25, 2021

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 4971-56-6, name is Furan-2,4(3H,5H)-dione, introducing its new discovery. Recommanded Product: 4971-56-6

A concise and scalable enantioselective total synthesis of the natural cardenolides cannogenol and cannogenol-3-O-alpha-l-rhamnoside has been achieved in 18 linear steps. The synthesis features a Cu(II)-catalyzed enantioselective and diastereoselective Michael reaction/tandem aldol cyclization and a one-pot reduction/transposition, which resulted in a rapid (6 linear steps) assembly of a functionalized intermediate containing C19 oxygenation that could be elaborated to cardenolide cannogenol. In addition, a strategy for achieving regio- and stereoselective glycosylation at the C3 position of synthetic cannogenol was developed and applied to the preparation of cannogenol-3-O-alpha-l-rhamnoside.

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Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Application of 7175-81-7, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.7175-81-7, Name is (S)-(Tetrahydrofuran-2-yl)methanamine, molecular formula is C5H11NO. In a article，once mentioned of 7175-81-7

Quaternary salt compounds of Formula (I) or pharmaceutically acceptable forms thereof, which are CCR2 antagonists and are useful in preventing, treating or ameliorating CCR2 mediated inflammatory syndromes, disorders or diseases in a subject in need thereof.

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Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Recommanded Product: 22929-52-8, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 22929-52-8, name is Dihydrofuran-3(2H)-one. In an article，Which mentioned a new discovery about 22929-52-8

The present invention provides compounds of Formula (I) and (II) as described herein, and salts thereof, and therapeutic uses of these compounds for treatment of disorders associated with Raf kinase activity. The invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds and a therapeutic co-agent.

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Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

453-20-3, Name is 3-Hydroxytetrahydrofuran, belongs to tetrahydrofurans compound, is a common compound. Safety of 3-HydroxytetrahydrofuranIn an article, once mentioned the new application about 453-20-3.

A serirs of 3-hydroxytetrahydrofuryl esters were synthesized.

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Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Chemistry is traditionally divided into organic and inorganic chemistry. SDS of cas: 13031-04-4, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 13031-04-4

Two conjugated polyketone reductases (CPRs) were isolated from Candida parapsilosis IFO 0708. The primary structures of CPRs (C1 and C2) were analyzed by amino acid sequencing. The amino acid sequences of both enzymes had high similarity to those of several proteins of the aldo-keto-reductase (AKR) superfamily. However, several amino acid residues in the putative active sites of AKRs were not conserved in CPRs-C1 and -C2.

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Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. COA of Formula: C5H8O3. Introducing a new discovery about 87392-07-2, Name is (S)-Tetrahydrofuran-2-carboxylic acid

The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.

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Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Related Products of 111769-27-8, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 111769-27-8, (R)-Tetrahydrofuran-3-amine 4-methylbenzenesulfonate, introducing its new discovery.

Described are compounds of Formula I which find utility in the treatment of cancer, autoimmune diseases and metabolic bone disorders through inhibition of c-FMS (CSF-1R), c-KIT, and/or PDGFR kinases. These compounds also find utility in the treatment of other mammalian diseases mediated by c-FMS, c-KIT, or PDGFR kinases.

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Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Application In Synthesis of (R)-(+)-2-Tetrahydrofuroic acid. Introducing a new discovery about 87392-05-0, Name is (R)-(+)-2-Tetrahydrofuroic acid

[Problem] antiviral action, particularly anti-influenza drugs effective as the polycyclic pyridone derivative compound. (1) a compound represented by the formula [a]. (H or a prodrug group P is formed, A1 The CR are independently1A R1B , O or S; A2 The CR2A ; A3 The CR are independently3A R3B , O or S; A4 The CR4A ; A5 The CR are independently5A R5B , O or S; A6 Is a single bond or a substituted or unsubstituted alkylene substituted with hetero atoms/may be interposed)[Drawing] no (by machine translation)

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Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Electric Literature of 13031-04-4, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 13031-04-4, 4,4-Dimethyldihydrofuran-2,3-dione, introducing its new discovery.

Novel, chiral Lewis base organocatalysts, which displayed poor enantioselection in the hydrosilylation of N-aryl beta-enamino esters, were found to be the catalysts of choice in the hydrosilylation of a-imino esters. In the presence of 10mol-% of the best catalyst, various a-imino esters under-went enantioselective hydrosilylation to provide a wide range of chiral a-amino esters with good, yields (up to 97%) and high enantioselectivities (up to 93 % ee) except for some special substrates.

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Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Application of 1679-47-6, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 1679-47-6, 3-Methyldihydrofuran-2(3H)-one, introducing its new discovery.

Monosubstituted gamma-lactols 1a-1c, 3a-3c and 4a-4c, as well as disubstituted gamma-lactol 5 and the gamma-hydroxy-substituted gamma-lactone 6, were transformed into disubstituted tetrahydrofuran derivatives by treatment with allyl- and propargylsilanes in the presence of Lewis acids. The diastereoselectivities were moderate to excellent and are interpreted by application of the Felkin-Anh model to cyclic oxocarbenium ions. The effects of the equilibria between conformers of the intermediates are discussed. The surprisingly high diastereoselectivity of 4-substituted gamma-lactols 3 can be explained on this basis.

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Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem