In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 7175-81-7, name is (S)-(Tetrahydrofuran-2-yl)methanamine, introducing its new discovery. Formula: C5H11NO
In this study, we developed an efficient and practical procedure for the synthesis of tetra-substituted Delta5-2-oxopiperazine that mimics the bioactive beta-turn structural motif of proteins. This synthetic route is robust and modular enough to accommodate four different substituents to obtain a high level of molecular diversity without any deterioration in stereochemical enrichment of the natural and unnatural amino acids. Through the in silico studies, including a distance calculation of side chains and a conformational overlapping of our model compound with a native beta-turn structure, we successfully demonstrated the conformational similarity of tetra-substituted Delta5-2-oxopiperazine to the beta-turn motif. For the library construction in a high-throughput manner, the fluorous tag technology was adopted with the use of a solution-phase parallel synthesis platform. A 140-membered pilot library of tetra-substituted Delta5-2- oxopiperazines was achieved with an average purity of 90% without further purification.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 7175-81-7, and how the biochemistry of the body works.Formula: C5H11NO
Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem