In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Quality Control of (R)-(+)-2-Tetrahydrofuroic acid, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 87392-05-0, name is (R)-(+)-2-Tetrahydrofuroic acid. In an article，Which mentioned a new discovery about 87392-05-0
The synthesis of the marine neurotoxin azaspiracid-1 has been accomplished. The individual fragments were synthesized by catalytic enantioselective processes: A hetero-Diels-Alder reaction to afford the E- and HI-ring fragments, a carbonyl-ene reaction to furnish the CD-ring fragment, and a Mukaiyama aldol reaction to deliver the FG-ring fragment. The subsequent fragment couplings were accomplished by aldol and sulfone anion methodologies. All ketalization events to form the nonacyclic target were accomplished under equilibrating conditions utilizing the imbedded configurations of the molecule to adopt one favored conformation. A final fragment coupling of the anomeric EFGHI-sulfone anion to the ABCD-aldehyde completed the convergent synthesis of (+)-azaspiracid-1.
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Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem