Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. SDS of cas: 89898-51-1. Introducing a new discovery about 89898-51-1, Name is Ethyl 4-oxotetrahydrofuran-3-carboxylate
Chiral Primary Amine Catalyzed Asymmetric alpha-Benzylation with In Situ Generated ortho-Quinone Methides
A dual activation strategy integrating primary amine catalysis and Lewis base activation has been developed for an asymmetric alpha-benzylation reaction. Enamines derived from beta-ketocarbonyls could react effectively with in situ generated ortho-quinone methides under Lewis base activation in asymmetric alpha-benzylation of beta-ketocarbonyls and alpha-branched aldehydes. The approach enables the creation of acyclic all-carbon quaternary stereocenters with excellent enantioselectivities and good activity.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.SDS of cas: 89898-51-1, you can also check out more blogs about89898-51-1
Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem