One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Computed Properties of C4H6O3, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 7331-52-4, Name is (S)-4-Hydroxydihydrofuran-2(3H)-one, molecular formula is C4H6O3
PROCESS FOR PREPARING OPTICALLY ACTIVE 2- 6-(HYDROXY-METHYL)-1,3-DIOXAN-4-YL]ACETIC ACID DERIVATIVES
The present invention is to provide a production technology by which an optically active 2-[6-(hydroxymethyl)-1,3-dioxan-4-yl]acetic acid derivative, which are of value as pharmaceutical intermediates, can be produced from inexpensive and readily available starting materials without using any extraordinary equipment such as an ultra-low-temperature reactor.The present invention is a production process of an optically active 2-[6-(hydroxymethyl)-1,3-dioxan-4-yl]acetic acid derivative, ???which comprises reacting an enolate, prepared by permitting a base or a 0-valent metal to act on an acetic acid ester derivative with (S)-beta-hydroxy-gamma-butyrolactone at a temperature not lower than -30C to give a dihydroxyoxohexanoic acid derivative,???treating the same with an acylating agent in the presence of a base to produce a dihydroxyoxohexanoic acid monoacyl derivative,???reducing this compound with a microorganism to produce a trihydroxyhexanoic acid monoacyl derivative,???treating this compound with an acetal-forming reagent in the presence of an acid catalyst to produce an acyloxymethyldioxanylacetic acid derivative, and, ???finally, subjecting this compound to solvolysis in the presence of a base.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Computed Properties of C4H6O3, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 7331-52-4, in my other articles.
Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem