One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Quality Control of 2,2-Dimethylsuccinicanhydride, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 17347-61-4, Name is 2,2-Dimethylsuccinicanhydride, molecular formula is C6H8O3
4-Phenoxypiperidine pyridazin-3-one histamine H3 receptor inverse agonists demonstrating potent and robust wake promoting activity
Structure-activity relationships for a series of phenoxypiperidine pyridazin-3-one H3R antagonists/ inverse agonists are disclosed. The search for compounds with improved hERG and DAT selectivity without the formation of in vivo active metabolites identified 6-[4-(1-cyclobutyl-piperidin- 4-yloxy)- phenyl]-4,4-dimethyl-4,5-dihydro-2H-pyridazin-3-one 17b. Compound 17b met discovery flow criteria, demonstrated potent H3R functional antagonism in vivo in the rat dipsogenia model and potent wake activity in the rat EEG/EMG model at doses as low as 0.1 mg/kg ip.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Quality Control of 2,2-Dimethylsuccinicanhydride, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 17347-61-4, in my other articles.
Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem