Properties and Exciting Facts About Tetrahydrofuran-3-carboxylic acid

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 89364-31-8

Synthetic Route of 89364-31-8, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.89364-31-8, Name is Tetrahydrofuran-3-carboxylic acid, molecular formula is C5H8O3. In a article,once mentioned of 89364-31-8

Effect of a phosphazene base on the diastereoselectivity of addition of alpha-sulfonyl carbanions to butyraldehyde and isopropylideneglyceraldehyde

The effect of tBuP4, a strong and cation-free base, on the yield and diastereoselectivity of additions of thus formed “naked” alpha-sulfonyl carbanions to achiral butyraldehyde and chiral isopropylideneglyceraldehyde was studied. It has been found that with tBuP4 a reasonable yield (?55%) and a slightly better diastereoselectivity (72% of the anti diastreomer) are obtained with achiral and nonfunctionalized butyraldehyde while with isopropylideneglyceraldehyde the use of tBuP4 allowed us to greatly increase the yields (up to 95-100%) and the diastereoselectivities (83-89% of a single diastereomer over the four possible diastereomers). It was also shown that the extra oxygen atom in the alpha-position plays a determinant role in this effect.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 89364-31-8

Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem