Application of 1679-47-6, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 1679-47-6, Name is 3-Methyldihydrofuran-2(3H)-one,introducing its new discovery.
Syntheses of Hydroxy Ketones from Lactones
gamma-Hydroxy ketones (4, n=2) are cleanly obtained by the addition of 1.1 equiv of n-butyllithium to gamma-lactones dissolved in ether at -90 deg C, since in these conditions the formation of diols by double organometallic attack is avoided, especially in the case of substituted lactones.The corresponding reactions performed in tetrahydrofuran are less satisfactory.The method cannot be applied to delta-valerolactone and epsilon-caprolactone, as well as to beta-lactones, from which extremely complex mixtures are obtained in low yields.Furthermore the reactions of Grignard reagentswith lactones in ether or in tetrahydrofuran are quite poor.From those lactones which behave unsatisfactorily toward n-butyllithium in ether, the corresponding beta-, delta-, and epsilon-hydroxy ketones (4, n=1, 3, 4) are prepared in two steps.The reactions with alpha,alpha-dilithioalkyl phenyl sulfones in tetrahydrofuran at low temperatures afford the omega-hydroxy-beta-keto sulfones (12), which are successively cleaved with aluminum amalgam to afford 4 in satisfactory overall yields.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 1679-47-6, and how the biochemistry of the body works.Application of 1679-47-6
Reference：
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem