Chemistry is traditionally divided into organic and inorganic chemistry. SDS of cas: 53558-93-3, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent,Which mentioned a new discovery about 53558-93-3
Zidovudine derivatives having antibacterial activity and its preparation method and application (by machine translation)
The invention discloses a Combivir derivative and its preparation method and application, which belongs to the antibacterial activity of the medicament with the synthesis technology field. The technical scheme of the present invention is to point: zidovudine derivatives having antibacterial activity, structural formula is:, wherein R is C1 – 4 Alkyl or a halogen atom. The invention also discloses the zidovudine derivatives having antibacterial activity of specific synthetic process and its application in preparing antibacterial drug. The invention according to zidovudine containing azido group in the molecule, by reacting it with click with different substituents of the aniline base alkyne apperception compound reaction to get zidovudine derivatives, and selecting the Staphylococcus aureus – gram positive bacteria, gram-negative bacteria and fungi – Escherichia coli – Candida albicans to the synthesized Combivir derivative of the in vitro antibacterial activity determination, the results show that the compounds demonstrate better antibacterial activity. (by machine translation)
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Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem