Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. category: Tetrahydrofurans. Introducing a new discovery about 4100-80-5, Name is 3-Methyldihydrofuran-2,5-dione
Efficient synthesis of spirolactones from cyclic anhydrides via an allylation/alkylation-RCM sequence
Starting from cyclic anhydrides the diallyl or dibutenyl lactones were obtained. The ring closing metathesis reaction of these using the Grubbs catalyst provided the corresponding spirolactones in good yields. With diallyl delta-lactone 2h, RCM occurred only in the presence of titanium tetraisopropoxide.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.category: Tetrahydrofurans, you can also check out more blogs about4100-80-5
Reference:
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem