Day: April 19, 2021

87392-07-2, Name is (S)-Tetrahydrofuran-2-carboxylic acid, belongs to tetrahydrofurans compound, is a common compound. Recommanded Product: (S)-Tetrahydrofuran-2-carboxylic acidIn an article, once mentioned the new application about 87392-07-2.

A high-optical-purity 1 – [tetrahydro-2-furyl] ethanone industrial preparation method (by machine translation)

The invention discloses a high-optical-purity 1 – [tetrahydro-2-furyl] ethanone industrial preparation method, belongs to the field of chemical synthesis, comprising the following steps: with tetrafuran formic acid as the raw material, reaction with carbonyl diimidazole, then adding malonic acid asian different propyl ester for condensation, then hydrolyzed in acidic conditions, the final extraction, concentrated to obtain product acetylprotoaescigenin tetrahydrofuran; the invention to prepare the high-optical-purity 1 – [tetrahydro-2-furyl] ethanone process, low cost of raw materials, do not need to use the Grignard reagent, stable product characteristics, the purity can be up to 98% or more, the optical purity can be up to 99% or more, the yield can reach 70% or more; the process after the actual commercial production verification, the quality is stable, mild reaction conditions, the operation is safe and reliable, process repeatability is good, the production cost is low, is a reliable high-optical-purity 1 – [tetrahydro-2-furyl] ethanone industrial preparation method. (by machine translation)

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Reference£º
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Electric Literature of 117752-82-6, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.117752-82-6, Name is (S)-3-Amino-gamma-butyrolactone hydrochloride, molecular formula is C4H8ClNO2. In a Article£¬once mentioned of 117752-82-6

Convenient synthesis of 3-(S)-amino-gamma-butyrolactone

An efficient two step conversion of N-t-Boc-L-aspartic acid beta-benzyl ester to enantiopure 3-(S)-amino-gamma-butyrolactone is described. In this route, chemoselective reduction of the alpha-carboxylic group in the starting material via a mixed anhydride with NaBH4 afforded the corresponding alcohol in 95% yield without any loss of the optical purity. Subsequent acidic hydrolysis of the N-protected beta-amino alcohol not only deprotected the amino group, but also produced the desired gamma-lactone in 98% yield with complete retention of the optical activity.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 117752-82-6

Reference£º
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Reference of 66838-42-4, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.66838-42-4, Name is (R)-Tetrahydrofuran-3-carboxylic acid, molecular formula is C5H8O3. In a Patent£¬once mentioned of 66838-42-4

Dihydro-Benzo-Oxazine and Dihydro-Pyrido-Oxazine Derivatives

The invention relates to dihydro-benzo-oxazine and dihydro-pyrido-oxazine compounds of the formula (I) and/or pharmaceutically acceptable salts and/or solvates thereof, wherein Y, V, W, U, Q, R1, R5, R7 and R30 are as defined in the description. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of the PI3K enzymes.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 66838-42-4, and how the biochemistry of the body works.Reference of 66838-42-4

Reference£º
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Synthetic Route of 19311-37-6, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.19311-37-6, Name is 3-Bromotetrahydrofuran, molecular formula is C4H7BrO. In a article£¬once mentioned of 19311-37-6

HETEROAROMATIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF

Provided herein are novel heteroaromatic derivatives, or a stereoisomer, a geometric isomer, a tautomer, an N-oxide, a hydrate, a solvate, a prodrug, a pharmaceutically acceptable salt or a prodrug thereof, and pharmaceutical compositions containing such compounds. Also provided herein are uses of such compounds or pharmaceutical compositions thereof in the manufacture of a medicament for treating respiratory diseases, especially chronic obstructive pulmonary disease (COPD).

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 19311-37-6

Reference£º
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Related Products of 453-20-3, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.453-20-3, Name is 3-Hydroxytetrahydrofuran, molecular formula is C4H8O2. In a Patent£¬once mentioned of 453-20-3

Aromatic polycyclic carboxylic acid derivatives (by machine translation)

The invention belongs to the field of medical technology, in particular to general formula (I) indicated by the aromatic ring carboxylic acid derivatives GPR40 receptor agonist, a pharmaceutically acceptable salt, an ester thereof or a stereoisomer thereof, wherein R1 , R2 , R3 , R4 And R5 Such as defined in the specification; the invention also relates to methods of preparing such compounds, pharmaceutical preparation and pharmaceutical composition, and the compounds and pharmaceutical compositions in the preparation as GPR40 receptor agonists for the prevention and/or for the treatment of diabetes in the application. (by machine translation)

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 453-20-3, and how the biochemistry of the body works.Related Products of 453-20-3

Reference£º
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Product Details of 52449-98-6, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 52449-98-6, Name is Oxolane-2-carbonyl chloride, molecular formula is C5H7ClO2

Process for the preparation of N-acyl-N-alkyl-2,6-dialkyl-3-chloroanilines

N-acyl-N-alkyl-2,6-dialkyl-3-chloroanilines of the formula STR1 wherein R1 is methyl or ethyl, R2 is alkoxymethyl, chloromethyl or 2-tetrahydrofuryl, R3 is alkoxymethyl, carboxy or alkoxycarbonyl and R4 is hydrogen or methyl and, if R3 is carboxy or alkoxycarbonyl, R4 is also 2-alkoxyethyl and 2-alkoxypropyl, and R3 and R4, together with the carbon atom to which both radicals are attached, may also form a 2-oxotetrahydro-3-furyl radical or a 2-oxo-5-methyltetrahydro-3-furyl radical, are prepared by reacting a 2,6-dialkylaniline of the formula STR2 with a halide of the formula STR3 wherein X is chlorine or bromine, to give an N-alkyl-2,6-dialkylaniline of the formula STR4 then converting said compound by further reaction with an acylating agent of the formula wherein X1 is chlorine, bromine or -O-CO-R2, into an N-acyl-N-alkyl-2,6-dialkylaniline of the formula STR5 and subsequently converting said compound by reaction with chlorine into an N-acyl-N-alkyl-2,6-dialkyl-3-chloroaniline of the above formula.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Product Details of 52449-98-6, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 52449-98-6, in my other articles.

Reference£º
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Electric Literature of 22929-52-8, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.22929-52-8, Name is Dihydrofuran-3(2H)-one, molecular formula is C4H6O2. In a article£¬once mentioned of 22929-52-8

Widely applicable background depletion step enables transaminase evolution through solid-phase screening

Directed evolution of transaminases is a widespread technique in the development of highly sought-after biocatalysts for industrial applications. This process, however, is challenged by the limited availability of effective high-throughput protocols to evaluate mutant libraries. Here we report a rapid, reliable, and widely applicable background depletion method for solid-phase screening of transaminase variants, which was successfully applied to a transaminase from Halomonas elongata (HEWT), evolved through rounds of random mutagenesis towards a series of diverse prochiral ketones. This approach enabled the identification of transaminase variants in viable cells with significantly improved activity towards para-substituted acetophenones (up to 60-fold), as well as tetrahydrothiophen-3-one and related substrates. Rationalisation of the mutants was assisted by determination of the high-resolution wild-type HEWT crystal structure presented herein.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 22929-52-8

Reference£º
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Formula: C5H10O2, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 15833-61-1, name is (Tetrahydrofuran-3-yl)methanol. In an article£¬Which mentioned a new discovery about 15833-61-1

Hydrogenation of furfural to butanol and pentanols for renewable gasoline blendstocks

Butanols and pentanols can be prepared in high selectivity from furfural reduction in a catalyzed continuous hydrogenation process. The catalyst should have bifunctional activity with both hydrogenation and acidic sites. A co-solvent is necessary to mitigate furfural plugging during extended operation. Both ethanol and hydroxymethyl tetrahydrofuran are suitable co-solvents. Hydroxymethyl tetrahydrofuran is an intermediate in the reduction of furfural to alcohols and higher overall yields from furfural can be obtained by recycling unreacted hydroxymethyl tetrahydrofuran for use as the reaction solvent.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 15833-61-1, help many people in the next few years.Formula: C5H10O2

Reference£º
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 165253-31-6, name is (Tetrahydrofuran-3-yl)methanamine, introducing its new discovery. Product Details of 165253-31-6

Preparation of amines

Disclosed is a process for the preparation of an amine by contacting in a reaction zone a water-soluble aldehyde, water, ammonia and hydrogen in the presence of a supported ruthenium catalyst at elevated temperature and pressure. The process is particularly useful for the preparation of 3-(aminomethyl)tetrahydrofuran by contacting an aqueous solution of 3-formyltetrahydrofuran with ammonia and hydrogen at elevated temperature and pressure in the presence of a supported ruthenium catalyst. The use of a supported ruthenium catalyst has been found to avoid the problem of catalyst leaching encountered when a nickel catalyst is used.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 165253-31-6, and how the biochemistry of the body works.Product Details of 165253-31-6

Reference£º
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem

Application of 5455-94-7, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 5455-94-7, 2,2,5,5-Tetramethyldihydrofuran-3(2H)-one, introducing its new discovery.

THE EFFECTS OF SUBSTITUENS AND SOLVENT POLARITY ON PHOTOCHEMICAL <1.3> SIGMATROPIC SHIFTS. EXPERIMENTAL EVIDENCE IN FAVOUR OF THE OCCURRENCE OF SUDDEN POLARIZATION IN ACYCLIC ALKENES

Furher experimental evidence regarding the occurence of sudden polarization in acyclic alkenes is presented.It is shown that the yield of formation of the product derived from an intramolecular photochemical <1,3>-OH shift in the 1 is dependent only on the polarity of the solvent employed.This result could be well explained in terms of a stabilization of the zwitterionic intermediate formed upon irradiation of 1 by reorientation polarization of the dipole solvent molecules.Besides this, it was found that replacement of the alkyl group at the terminal carbon atom of the C3-C9 exocyclic double bond in 1 by a phenyl substituent led to the occurence of a photochemical <1.3>-H shift.This directive effect of the substituents at the exocyclic double bond could be well explained on the basis of the sudden polarization model.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Application of 5455-94-7. In my other articles, you can also check out more blogs about 5455-94-7

Reference£º
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem