Synthetic Route of 1679-47-6, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.1679-47-6, Name is 3-Methyldihydrofuran-2(3H)-one, molecular formula is C5H8O2. In a Article£¬once mentioned of 1679-47-6
Iridium-catalyzed asymmetric hydrogenation of racemic alpha-substituted lactones to chiral diols
We report a protocol for the highly efficient iridium-catalyzed asymmetric hydrogenation of racemic alpha-substituted lactones via dynamic kinetic resolution. Using Ir-SpiroPAP (R)-1d as a catalyst, a wide range of chiral diols were prepared in a high yield (80-95%) with a high enantioselectivity (up to 95% ee) under mild reaction conditions. This protocol was used for enantioselective syntheses of (?)-preclamol and a chiral 2,5-disubstituted tetrahydropyran.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 1679-47-6, and how the biochemistry of the body works.Synthetic Route of 1679-47-6
Reference£º
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem