Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 79-50-5, Name is 3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one, molecular formula is C6H10O3, belongs to Tetrahydrofurans compound. In a document, author is Rizk, Mohamed Mohamed Salem, introduce the new discover, SDS of cas: 79-50-5.
A Rapid and reliable thin-layer chromatographic method for the simultaneous estimation of celecoxib and diacerein in their binary mixture using nanosilica gel plate
A novel, rapid, and sensitive stability-indicating high-performance thin-layer chromatography method was developed and validated for the simultaneous determination of celecoxib (CEL) and diacerein (DIA) in bulk and a capsule binary mixture. The complete separation was achieved by the proposed method on nanosilica gel F-254 plates using n-hexane-ethyl acetate-tetrahydrofuran-glacial acetic acid (7:3:1:0.8, V/V) as the mobile phase. The chromatographic bands were visualized using short-wave ultraviolet light, and the amount of CEL and DIA was determined by scanning densitometry at 254 nm using the peak area. The R-F values were 0.59 and 0.37 for CEL and DIA, respectively. From regression plots, it was found that good linearity was achieved in the concentration ranges of 20.00-320.00 ng/band and 5.00-80.00 ng/band with mean percentage recoveries 99.86 +/- 0.70 and 99.64 +/- 0.96 for CEL and DIA, respectively. The proposed method was validated according to the International Conference on Harmonisation guidelines. The statistical analysis of the results revealed high accuracy and precision, the suggested procedures could be used as a stability-indicating assay for the simultaneous determination of CEL and DIA in bulk drug and their capsule binary mixture in the presence of their degradation products.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 79-50-5. SDS of cas: 79-50-5.
Reference:
Tetrahydrofuran – Wikipedia,
,Tetrahydrofuran | (CH2)3CH2O – PubChem