Day: March 26, 2021

Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Song, Shaofei, once mentioned the application of 79-50-5, Name is 3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one, molecular formula is C6H10O3, molecular weight is 130.14, MDL number is MFCD00064333, category is Tetrahydrofurans. Now introduce a scientific discovery about this category, Quality Control of 3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one.

Crystallization-Driven Self-Assembly of a Block Copolymer with Amphiphilic Pendant Groups

Crystalline-coil block copolymers (BCPs) with an amphiphilic corona-forming block broaden the range of solvents in which crystallization-driven self-assembly experiments can be carried out. These materials allow one to examine how rather large changes in solvent polarity can affect the self-assembly process, leading to novel uniform structures. Here, we describe the synthesis and self-assembly properties of a crystalline-brush BCP, PFS27-b-P(EG-E) MA(48) (PFS, poly(ferrocenyldimethylsilane), and P(EG-E)MA, poly(tetraethylene glycol monododecyl ether methacrylate); the subscripts refer to the mean degrees of polymerization). Tetrahydrofuran (THF) is a common good solvent for both blocks, whereas the corona polymer itself is soluble in alcohols ranging from 2-propanol to 1-decanol and in octane and decane. Self-assembly in 2-propanol was normal, forming long (>5 mu m) fiber-like micelles of uniform width when the polymer suspended in solvent was heated (i.e., 80 degrees C) and cooled. Micelles of similar width but uniform and variable length were obtained when micelle fragments were subjected to seeded growth or self-seeding conditions. In primary alcohols (1-butanol to 1-decanol), direct self-assembly led to uniform scarf-like structures (total length similar to 2 mu m) in which the length of the central platelet increased with the carbon number in the solvent, offset by shorter fiber-like protrusions at the ends. We speculate that these changes are related to the temperature at which core crystallization occurred as the samples cooled. Selfassembly in decane was more complicated. Large (>10 mu m) aggregated structures consisting of fiber bundles formed initially. Sonication followed by seeded growth with additional BCP or self-seeding led to relatively uniform elongated lenticular micelles, substantially wider than those formed under these protocols for this BCP in 2-propanol. Solvent polarity has a profound effect on the self-assembly of this BCP with a brush-like amphiphilic corona-forming block.

Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 79-50-5, Quality Control of 3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one.

Reference:
Tetrahydrofuran – Wikipedia,
,Tetrahydrofuran | (CH2)3CH2O – PubChem

Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 79-50-5, Name is 3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one, molecular formula is C6H10O3, belongs to Tetrahydrofurans compound. In a document, author is Rizk, Mohamed Mohamed Salem, introduce the new discover, SDS of cas: 79-50-5.

A Rapid and reliable thin-layer chromatographic method for the simultaneous estimation of celecoxib and diacerein in their binary mixture using nanosilica gel plate

A novel, rapid, and sensitive stability-indicating high-performance thin-layer chromatography method was developed and validated for the simultaneous determination of celecoxib (CEL) and diacerein (DIA) in bulk and a capsule binary mixture. The complete separation was achieved by the proposed method on nanosilica gel F-254 plates using n-hexane-ethyl acetate-tetrahydrofuran-glacial acetic acid (7:3:1:0.8, V/V) as the mobile phase. The chromatographic bands were visualized using short-wave ultraviolet light, and the amount of CEL and DIA was determined by scanning densitometry at 254 nm using the peak area. The R-F values were 0.59 and 0.37 for CEL and DIA, respectively. From regression plots, it was found that good linearity was achieved in the concentration ranges of 20.00-320.00 ng/band and 5.00-80.00 ng/band with mean percentage recoveries 99.86 +/- 0.70 and 99.64 +/- 0.96 for CEL and DIA, respectively. The proposed method was validated according to the International Conference on Harmonisation guidelines. The statistical analysis of the results revealed high accuracy and precision, the suggested procedures could be used as a stability-indicating assay for the simultaneous determination of CEL and DIA in bulk drug and their capsule binary mixture in the presence of their degradation products.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 79-50-5. SDS of cas: 79-50-5.

Reference:
Tetrahydrofuran – Wikipedia,
,Tetrahydrofuran | (CH2)3CH2O – PubChem

Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 63-42-3, Name is Lactose, molecular formula is , belongs to tetrahydrofurans compound. In a document, author is Chi, H. Y., Computed Properties of C12H22O11.

Fabrication of polylactic acid/paclitaxel nano fibers by electrospinning for cancer therapeutics

Polylactic acid (PLA) is a thermoplastic and biodegradable polyester, largely derived from renewable resources such as corn starch, cassava starch and sugarcane. However, PLA is only soluble in a narrow range of solvents such as tetrahydrofuran, dioxane, chlorinated solvents and heated benzene. The limited choices of solvent for PLA dissolution have imposed significant challenges in the development of specifically engineered PLA nanofibers with electrospinning techniques. Generally, the electrospun polymeric materials have been rendered with unique properties such as high porosity and complex geometry while maintaining its biodegradability and biocompatibility for emerging biomedical applications. In this study, a new anticancer drug delivery system composed of PLA nanofibers with encapsulated paclitaxel was developed by the electrospinning of the respective nanofibers on top of a spin-coated thin film with the same chemical compositions. Our unique approach is meant for promoting strong bonding between PLA-based nanofibers and their respective films in order to improve the prolonged release properties and composite film stability within a fluctuative physiochemical environment during cell culture. PLA/paclitaxel nanofiber supported on respective polymeric films were probed by scanning electronic microscope, Fourier transform infrared spectrometer and water contact measurement for determining their surface morphologies, fibers’ diameters, molecular vibrational modes, and wettability, respectively. Moreover, PLA/paclitaxel nanofibers supported on respective spin-coated films at different loadings of paclitaxel were evaluated for their abilities in killing human colorectal carcinoma cells (HCT-116). More importantly, MTT assays showed that regardless of the concentrations of paclitaxel, the growth of HCT-116 was effectively inhibited by the prolonged release of paclitaxel from PLA/paclitaxel nanofibers. An effective prolonged delivery system of paclitaxel based on PLA nanofiber-based film has demonstrated exciting potentials for emerging applications as implantable drug delivery patch in post-surgical cancer eradication.

If you are hungry for even more, make sure to check my other article about 63-42-3, Computed Properties of C12H22O11.

Reference:
Tetrahydrofuran – Wikipedia,
,Tetrahydrofuran | (CH2)3CH2O – PubChem

Reference of 19444-84-9, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 19444-84-9, Name is 3-Hydroxydihydrofuran-2(3H)-one, SMILES is OC1CCOC1=O, belongs to tetrahydrofurans compound. In a article, author is de Oliveira, Edison Rogerio Marques, introduce new discover of the category.

Optimal Experimental Conditions for Improving the Yield of Poly(limonene) from Photoinduced Polymerization

Limonene represents a possible candidate for the synthesis of polymers from renewable sources. However, because of some structural characteristics, the process yield tends to be considerably low (< 10%). In this sense, the evaluation of still unexplored alternative controlled strategies of synthesis, together with techniques of process optimization, can enable the increase in the polymer yield. Taking this into consideration, this study presents, for the first time, the optimal conditions for maximizing the poly(limonene) yield using a photoinduced polymerization route. The reactions were all conducted at a mild temperature (40 degrees C) and the polymer was characterized by nuclear magnetic resonance (H-1-NMR and C-13-NMR). A face-centered design (FCD) was proposed for interpreting the effects of the reagent ratio (initiator, catalyst, and electron donor amine) on the polymerization. The monomer molar ratio was set to 100 with 6 h of polymerization time. All reagents exerted significant and positive effects on the yield, with the initiator having the most pronounced effect. The optimal conditions for maximizing the yield were as follows: molar ratios of the electron donor amine (PMDETA): 5-8.5; catalyst (TX): 1-1.7; and initiator (TBE): 1.7. Thus, similar to 18% yield could be achieved using a molar ratio of 100:8.5:1.7:1.7 (monomer:PMDETA:TX:TBE). It was observed that the polymer had good adhesion to steel when dried and moderate adhesion to glass. The polymer was insoluble in water and soluble in ethanol, tends to form suspension in solution of ethanol/water, in addition to being partially soluble in tetrahydrofuran and chloroform. These characteristics indicate that the material prepared herein is a promising renewable additive for coatings, films, or adhesives. [GRAPHICS] . Reference of 19444-84-9, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 19444-84-9 is helpful to your research.

Reference:
Tetrahydrofuran – Wikipedia,
,Tetrahydrofuran | (CH2)3CH2O – PubChem

Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 96-82-2, Name is Lactobionic acid, molecular formula is C12H22O12, belongs to tetrahydrofurans compound. In a document, author is Soszka, Emilia, introduce the new discover, SDS of cas: 96-82-2.

Ni-Pd/gamma-Al2O3 Catalysts in the Hydrogenation of Levulinic Acid and Hydroxymethylfurfural towards Value Added Chemicals

gamma-Al2O3 supported Ni-Pd catalysts with different Ni:Pd ratios were studied in the hydrogenation of two industrially-relevant platform molecules derived from biomass, namely levulinic acid and hydroxymethylfurfural. The bimetallic catalysts showed better performances in both processes in comparison to the monometallic counterparts, for which a too strong interaction with the alumina support reduced the activity. The behavior of the bimetallic catalysts was dependent on the Ni:Pd ratio, and interestingly also on the targeted hydrogenation reaction. The Pd-modified Ni-rich system behaves like pure Ni catalyst, but with a strongly boosted activity due to a higher number of Ni active sites available, Pd being considered as a spectator. This high activity was manifested in the levulinic acid hydrogenation with formic acid used as an internal hydrogen source. This behavior differs from the case of the Pd-rich system modified by Ni, which displayed a much higher Pd dispersion on the support compared to the monometallic Pd catalyst. The higher availability of the Pd active sites while maintaining a high surface acidity allows the catalyst to push the HMF hydrodeoxygenation reaction forward towards the green biopolymer precursor 2,5-bis(hydroxymethyl)-tetrahydrofuran, and in consequence to strongly modify the selectivity of the reaction. In that case, residual chlorine was proposed to play a significant role, while Ni was considered as a spectator.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 96-82-2. SDS of cas: 96-82-2.

Reference:
Tetrahydrofuran – Wikipedia,
,Tetrahydrofuran | (CH2)3CH2O – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 7331-52-4, Name is (S)-4-Hydroxydihydrofuran-2(3H)-one, formurla is C4H6O3. In a document, author is Elahi, Fazal, introducing its new discovery. Computed Properties of C4H6O3.

Speciation and determination of chromium by ultrasound-assisted deep eutectic solvent liquid-liquid microextraction followed by flame atomic absorption spectrometry

In the present study, an ultrasound-assisted deep eutectic solvent liquid-liquid microextraction (UA-DES-LLME) technique was developed for selective speciation, extraction, and preconcentration of chromium species followed by quantitation by flame atomic absorption spectrometry. The effective parameters of the applied method comprising pH, composition and volume of the deep eutectic, volume of ammonium pyrrolidine dithiocarbamate complexing agent, volume of tetrahydrofuran, time of ultrasonication and centrifugation were optimized. The proposed method at optimum values of all factors was used for determination of Cr(VI). For evaluation of total chromium species, added KMnO4(strong oxidizing agent) into the sample, and heated for 2 min to convert Cr(III) into Cr(VI) and determined. The Cr(III) concentration was obtained from the difference between Cr(VI) from total chromium. Under the optimal conditions, preconcentration factor (PF), limit of detection (LOD), and limit of quantification (LOQ) were found as 50, 0.8 mu g L(-1)and 3.2 mu g L-1, respectively. The relative standard deviation (RSD %) was found < 5.0%. Finally, the developed method was used for the determination of Cr(VI) and Cr(III) in tea and water samples. If you are hungry for even more, make sure to check my other article about 7331-52-4, Computed Properties of C4H6O3.

Reference:
Tetrahydrofuran – Wikipedia,
,Tetrahydrofuran | (CH2)3CH2O – PubChem

Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 3188-00-9, Name is 2-Methyltetrahydrofuran-3-one, molecular formula is C5H8O2, belongs to tetrahydrofurans compound. In a document, author is Lee, Seulah, introduce the new discover, Formula: C5H8O2.

Calvatianone, a Sterol Possessing a 6/5/6/5-Fused Ring System with a Contracted Tetrahydrofuran B-Ring, from the Fruiting Bodies of Calvatia nipponica

Calvatia nipponica is an extremely rare mushroom with a limited number of studies on its chemical components and biological activities published. Here we report the isolation of a novel sterol, calvatianone (1), possessing a 6/5/6/5-fused ring system with a contracted tetrahydrofuran B-ring, and four known steroids (2-5) from the fruiting bodies of C. nipponica. The structure of calvatianone including its absolute configuration was determined by NMR spectroscopic analyses, HR-ESIMS, gauge-including atomic orbital NMR chemical shift calculations, and ECD calculations. Ergosterol peroxide (3) and cyathisterol (4) suppressed the cell viability increase induced by 17 beta-estradiol in MCF-7 breast cancer cell lines, suggesting a possible approach for these compounds to serve as ER alpha antagonists.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 3188-00-9. Formula: C5H8O2.

Reference:
Tetrahydrofuran – Wikipedia,
,Tetrahydrofuran | (CH2)3CH2O – PubChem

Chemistry is an experimental science, Name: 2-Methyltetrahydrofuran-3-one, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 3188-00-9, Name is 2-Methyltetrahydrofuran-3-one, molecular formula is C5H8O2, belongs to tetrahydrofurans compound. In a document, author is Soares, Vitor.

Umbelliferone esters with antibacterial activity produced by lipase-mediated biocatalytic pathway

Objective The present report describes the enzymatic acylation of umbelliferone with different vinyl esters as acyl donors biocatalyzed by the commercial lipase Novozym (R) 435, and the investigation for their antibacterial activity against ATCC and clinical strains isolated from hospital infection sites. Results The umbelliferone esters (1-5) were synthesized through the acylation reaction of 7-hydroxy-2H-chromen-2-one with different long chain vinyl esters catalyzed by the lipase Novozym 435. The reaction conditions were: 10% Novozym 435; tetrahydrofuran:acetone (3:1) for the reactions with acetate, propionate and butyrate vinyl esters 50-90% conversion, and (9:1) for decanoate and laurate vinyl esters 10-15% conversion; acyl donor/umbelliferone molar ratio of 10:1 and 60 degrees C. All the umbelliferone esters were characterized NMR and (HRMS). The antibacterial activity of the products were tested using the broth microdilution method in order to determine the minimum inhibitory concentration (MIC). The results displayed by 7-laurate and 7-decanoate-umbelliferone esters showed the highest antibacterial potential, with 1 mM inhibitory activity for ATCC 33591, a methicillin and oxacillin resistantStaphylococcus aureusstrain. They were also able to inhibit gram-negative bacterial strains, such asPseudomonas aeruginosa(MIC 0.5 mM) andKlebsiella pneumoniae(MIC 1 mM). In addition, 7-laurate- and 7-decanoate-umbelliferone esters were able to inhibit all clinical strains (MIC 1 mM; except 7-laurate-umbelliferone in which MIC 0.5 mM against 55a). Conclusions This is the first study performing the biocatalysis of umbelliferone followed by the purification of the products and the antibacterial evaluation.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 3188-00-9, in my other articles. Name: 2-Methyltetrahydrofuran-3-one.

Reference:
Tetrahydrofuran – Wikipedia,
,Tetrahydrofuran | (CH2)3CH2O – PubChem

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 706-14-9, Name is gamma-Decanolactone, molecular formula is C10H18O2. In an article, author is Llopis, Natalia,once mentioned of 706-14-9, Product Details of 706-14-9.

HFIP-Promoted Synthesis of Substituted Tetrahydrofurans by Reaction of Epoxides with Electron-Rich Alkenes

In the present work, the employment of fluorinated alcohols, specifically 1,1,1,3,3,3-hexafluoroisopropanol (HFIP), as solvent and promoter of the catalyst-free synthesis of substituted tetrahydrofuranes through the addition of electron-rich alkenes to epoxydes is described. The unique properties of this fluorinated alcohol, which is very different from their non-fluorinated analogs, allows carrying out this new straightforward protocol under smooth reaction conditions affording the corresponding adducts in moderate yields in the majority of cases. Remarkably, this methodology has allowed the synthesis of new tetrahydrofuran-based spiro compounds as well as tetrahydrofurobenzofuran derivatives. The scope and limitations of the process are also discussed. Mechanistic studies were also performed pointing towards a purely ionic or a S(N)2-type process depending on the nucleophilicity of the alkene employed.

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Reference:
Tetrahydrofuran – Wikipedia,
,Tetrahydrofuran | (CH2)3CH2O – PubChem

Electric Literature of 19444-84-9, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 19444-84-9, Name is 3-Hydroxydihydrofuran-2(3H)-one, SMILES is OC1CCOC1=O, belongs to tetrahydrofurans compound. In a article, author is Mohammadi, Mojtaba, introduce new discover of the category.

CNC dispersion in PLA and PBAT using two solvents: morphological and rheological properties

Cellulose nanocrystals (CNCs) were dispersed via solution casting in amorphous (A) and semi-crystalline (SC) poly (lactic acid) (PLA) and poly (butylene adipate-co-terephthalate) (PBAT). The protocol, optimized following the Hansen solubility parameter theory, relies on binary mixtures of tetrahydrofuran and dimethyl sulfoxide for the polymers and CNCs, respectively. First highlighted through atomic force microscopy, good filler dispersion and distribution were confirmed by a decrease of the linear viscoelastic region and significant increases of the complex viscosity, storage modulus, and apparent yield stress of the nanocomposites with CNC content, specifically at low frequencies. CNC percolation thresholds of 1, 0.3, and 0.3 wt% were determined in A-PLA, SC-PLA, and PBAT, respectively. These are the lowest to be reported in the literature until now. While PLA retained solvent traces, leading to a significant plasticizing effect, solvent removal was complete in PBAT. It was attributed to the crystallization of PBAT at the drying temperature (70 degrees C).

Electric Literature of 19444-84-9, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 19444-84-9 is helpful to your research.

Reference:
Tetrahydrofuran – Wikipedia,
,Tetrahydrofuran | (CH2)3CH2O – PubChem