Let¡¯s face it, organic chemistry can seem difficult to learn. Especially from a beginner¡¯s point of view. Like 79-50-5, Name is 3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one. In a document, author is Mou, Zehuai, introducing its new discovery. Category: Tetrahydrofurans.
An efficient and green method to prepare bis-alpha-hydroxy phosphonates using triethylamine as catalyst
An efficient, convenient and environmentally friendly method for the synthesis of bis-alpha-hydroxy phosphonatesviaa perfectly atom economical Pudovik reaction is described. Using 5 mol% of triethylamine as a catalyst, a series of aromatic/heteroaromatic dialdehydes reacts with dialkyl phosphites to afford the corresponding bis-alpha-hydroxy phosphonates, particularly the bio-mass based ones, under solvent-free conditions or in a minimum amount of tetrahydrofuran at room temperature with moderate to excellent yields (52-95%).
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 79-50-5 help many people in the next few years. Category: Tetrahydrofurans.
Reference:
Tetrahydrofuran – Wikipedia,
,Tetrahydrofuran | (CH2)3CH2O – PubChem