Reference of 97-99-4, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 97-99-4, Name is (Tetrahydrofuran-2-yl)methanol, SMILES is OCC1OCCC1, belongs to Tetrahydrofurans compound. In a article, author is Zhu, Xiancui, introduce new discover of the category.
Dehydrogenative Coupling of Terminal Alkynes with O/N-Based Monohydrosilanes Catalyzed by Rare-Earth Metal Complexes
Newly synthesized rare-earth metal alkyl complexes bearing a tripyrrolyl ligand act as excellent precatalysts for the cross-dehydrogenative coupling between various terminal alkynes and O/N-based monohydrosilanes of HSi(OEt)(3)/HSi(NMe2)(3), leading to the formation of a variety of alkoxysilylalkyne and aminosilylalkyne derivatives in good to high yields. The precatalysts LRE(CH2SiMe3)(thf)(2) (RE = Y(1a), Er(1b), Yb(1c), L = 2,5-[(2-C4H3N)CPh2](2)(C4H2NMe), thf = tetrahydrofuran) were easily prepared in high yields via the reactions of RE(CH2SiMe3)(3)(thf)(2) with the proligand H2L in a single step. Mechanistic studies reveal that treatment of 1 with phenylacetylene could generate the active catalytic species: dinuclear rare-earth metal alkynides (L(thf)(n)[RE(mu-C CPh)](2)L) (RE = Y(5a), n = 1; Yb(5c), n = 0), which could react with HSi(OEt)(3) to produce the coupling product 4aa and the dinuclear rare-earth metal hydrides (L (thf)[RE(mu-H)](2)L) (RE = Y(6a); Yb(6c)). By contrast, prior treatment of 1c with HSi(OEt)(3) proceeds via cleavage of the Si-O bond to produce the dinuclear ytterbium alkoxide (LYb(mu-OEt))(2) 7c, which is inert in the dehydrogenative coupling reaction. The results of the mechanistic studies are consistent with the observation that the reaction is greatly influenced by the addition sequence of precatalyst/alkynes/silanes.
Reference of 97-99-4, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 97-99-4 is helpful to your research.
Reference:
Tetrahydrofuran – Wikipedia,
,Tetrahydrofuran | (CH2)3CH2O – PubChem